http://en.wikipedia.org/wiki/Mitochondrion
Mitochondrion
.- In cell biology, a mitochondrion (plural mitochondria)
is a membrane-enclosed organelle found in most eukaryotic cells.[1] These organelles range from 0.5 to
1.0 micrometer (μm) in diameter. Mitochondria are sometimes
described as "cellular power plants" because they generate most of
the cell's supply of adenosine
triphosphate (ATP),
used as a source of chemical energy.[2] In addition to supplying cellular energy, mitochondria are involved in
a range of other processes, such as signaling, cellular
differentiation, cell death, as well as the control of the cell cycle and cell growth.[3] Mitochondria have been implicated in several human diseases, including mitochondrial
disorders[4] and cardiac dysfunction,[5] and may play a role in the aging process. The word mitochondrion comes from the Greek
μίτος mitos, thread, + χονδρίον chondrion, granule.
Several characteristics make mitochondria unique. The number of
mitochondria in a cell varies widely by organism and tissue type. Many cells have only a single mitochondrion, whereas others can
contain several thousand mitochondria.[6][7] The
organelle is composed of compartments that carry out specialized functions.
These compartments or regions include the outer
membrane, the intermembrane
space, the inner
membrane, and the cristae and matrix. Mitochondrial proteins vary depending on the tissue and the species.
In humans, 615 distinct types of proteins have been identified from cardiac mitochondria,[8] whereas
in Murinae (rats),
940 proteins encoded by distinct genes have been reported.[9] The
mitochondrial proteome is
thought to be dynamically regulated.[10] Although
most of a cell's DNA is contained in the cell nucleus, the mitochondrion has its own independent genome.
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